Transmucosal Drug Delivery

Transmucosal Drug Delivery
Pharmaceutical materials are classified into 2 categories, i.e., the active moieties and the excipients. Both play an important role in conventional and novel drug delivery performances. Since, goal of the drug delivery is to optimize the therapeutics efficacy of the drug by optimal delivery to the sites of action with minimizing adverse effects. This can be achieved by using an appropriate set condition to allow the active moieties and excipients in the drug delivery systems properly function. The transmucosal routes of drug delivery offer distinct advantages over peroral administration for systemic drug delivery such as possible bypass of the first pass effect and avoidance of presystemic elimination within the GI tract. Therefore, both in vitro physico-chemical characterisation as well as in vivo characterisation is required during investigation. Not only the therapeutic achievement, but also the key approach to the excellent drug products in terms of appearance and stability can be obtained. The research in transmucosal delivery is aimed to investigate novel pharmaceutical materials or formulations that contribute to the release both in vitro and in vivo at the target sites of action, as well as the stability of the drug. Particular attention is given to new approaches which can extend dosage form retention time or can be engineered to deliver complex molecules such as proteins and peptides as well as natural products. In addition, pharmacokinetic basis of the drug is integrated to investigate the drug bioavailability as well as its clinical performance.

Research staff
• Prof. Dr. Vimon Tantishaiyakul, Department of Pharmaceutical Chemistry
• Prof. Dr. Damrongsak Faroongsarng, Department of Pharmaceutical Technology
• Assoc. Prof. Dr. Sanae Kaewnopparat, Department of Pharmaceutical Technology
• Assoc. Prof. Nattha Kaewnopparat, Department of Pharmaceutical Technology
• Assist. Prof. Dr. Chitchamai Ovatlarnporn, Department of Pharmaceutical Chemistry

©2016 Drug Delivery System Excellence Center

Faculty of Pharmaceutical Sciences, Prince of Songkla University
Tel. +66(0) 7428 8979 Fax. +66(0) 7428 8979
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