Member : Member
Academic Rank : Assistant Professor
Research Area : protein chemistry and medicinal enzymology
Researcher Profile
Born: 1966
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Academic Rank: Assistant Professor
Education:
2000 Ph.D.(Medicinal Chemistry), University of North Carolina at Chapel Hill, USA
1994 M.Sc. in Pharmacy, Chulalongkorn University, Thailand
1991 B.Sc. in Pharmacy (First Class Honors), Prince of Songkla University, Thailand
Scientific Interest:
Structure-based drug design, protein chemistry, medicinal enzymology
Publication Summary
Journal Articles
H-index
Citation
Journal Articles:
John, S., Canyuk, B., Anand, T.C.V., Sukasem, C. and Pat-Tharachayakul, S. Patient, Disease, and Drug-Related Risk Factors Associated with Pheny-toin-Induced Cutaneous Adverse Drug Reactions in South Indian Epileptic Patients-A Prospective Case-Control Study. Current Drug Safety, 17(3): 241-249, 2022.
John, S., Balakrishnan, K., Sukasem, C., Anand, T.C.V., Canyuk, B., Pattharachayakul, S. Association of HLA-B*51:01, HLA-B*55:01, CYP2C9*3, and phenytoin-induced cutaneous adverse drug reactions in the south indian tamil population (2021) Journal of Personalized Medicine, 11 (8), art. no. 737, .
Ungcharoenwiwat, P., Canyuk, B., H-Kittikun, A. Synthesis of jatropha oil based wax esters using an immobilized lipase from Burkholderia sp. EQ3 and Lipozyme RM IM (2016) Process Biochemistry, 51 (3), pp. 392-398.
Ratanaphan, A., Canyuk, B. Host cell reactivation and transcriptional activation of carboplatin-modified BRCA1 (2014) Breast Cancer: Basic and Clinical Research, 8 (1), pp. 51-56.
Ratanaphan, A., Panomwan, P., Canyuk, B., Maipang, T. Identification of novel intronic BRCA1 variants of uncertain significance in a Thai hereditary breast cancer family (2011) Journal of Genetics, 90 (2), pp. 327-331.
Sontimuang, C., Suedee, R., Canyuk, B., Phadoongsombut, N., Dickert, F.L. Development of a rubber elongation factor, surface-imprinted polymer-quartz crystal microbalance sensor, for quantitative determination of Hev b1 rubber latex allergens present in natural rubber latex products (2011) Analytica Chimica Acta, 687 (2), pp. 184-192.
Atipairin, A., Canyuk, B., Ratanaphan, A. Substitution of aspartic acid with glutamic acid at position 67 of the BRCA1 RING domain retains ubiquitin ligase activity and zinc(II) binding with a reduced transition temperature (2011) Journal of Biological Inorganic Chemistry, 16 (2), pp. 217-226.
Atipairin, A., Canyuk, B., Ratanaphan, A. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by the platinum-based anticancer drugs (2011) Breast Cancer Research and Treatment, 126 (1), pp. 203-209.
Atipairin, A., Canyuk, B., Ratanaphan, A. Cisplatin affects the conformation of apo form, not holo form, of BRCA1 RING finger domain and confers thermal stability (2010) Chemistry and Biodiversity, 7 (8), pp. 1949-1967.
Ratanaphan, A., Wasiksiri, S., Canyuk, B., Prasertsan, P. Cisplatin-damaged BRCA1 exhibits altered thermostability and transcriptional transactivation (2009) Cancer Biology and Therapy, 8 (10), pp. 890-898.
Suedee, R., Seechamnanturakit, V., Suksuwan, A., Canyuk, B. Recognition properties and competitive assays of a dual dopamine/serotonin selective molecularly imprinted polymer (2008) International Journal of Molecular Sciences, 9 (12), pp. 2333-2356.
Canyuk, B., E-Wan, A., Keawwijit, W., Nualnoi, T., Sirisatean, L., Tansakul, P., Tanthana, C. The role for glutamic acid at position 196 in human hypoxanthine phosphoribosyltransferase (HPRT) as investigated using site-directed mutagenesis (2008) Nucleosides, Nucleotides and Nucleic Acids, 27 (6-7), pp. 894-899.
Suedee, R., Seechamnanturakit, V., Canyuk, B., Ovatlarnporn, C., Martin, G.P. Temperature sensitive dopamine-imprinted (N,N-methylene-bis-acrylamide cross-linked) polymer and its potential application to the selective extraction of adrenergic drugs from urine (2006) Journal of Chromatography A, 1114 (2), pp. 239-249.
Ratanaphan, A., Canyuk, B., Wasiksiri, S., Mahasawat, P. In vitro platination of human breast cancer suppressor gene1 (BRCA1) by the anticancer drug carboplatin (2005) Biochimica et Biophysica Acta - General Subjects, 1725 (2), pp. 145-151.
Canyuk, B., Medrano, F.J., Wenck, M.A., Focia, P.J., Eakin, A.E., Craig III, S.P. Interactions at the Dimer Interface Influence the Relative Efficiencies for Purine Nucleotide Synthesis and Pyrophosphorolysis in a Phosphoribosyltransferase (2004) Journal of Molecular Biology, 335 (4), pp. 905-921.
Canyuk, B., Focia, P.J., Eakin, A.E. The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography (2001) Biochemistry, 40 (9), pp. 2754-2765.
Canyuk, B., Craig III, S.P., Eakin, A.E. Bacterial complementation as a means to test enzyme-ligand interactions (1998) Applied Microbiology and Biotechnology, 50 (2), pp. 181-186.
Craig, S.P., Canyuk, B., Sigmon, K.A., Lee, C.C. Studies of residues involved in substrate binding and catalysis in hypoxanthine phosphoribosyltransferases (1997) FASEB Journal, 11 (9), .
Canyuk, B., Craig III, S.P., Eakin, A.E. A microtiter plate method using bacterial complementation to identify compounds that bind to the active site of hypoxanthine phosphoribosyltransferases (HPRTs) (1997) Protein Engineering, 10 (3333), p. 81.
