Visiting Professors

Bijon Kumar Sil

Bijon Kumar Sil

Member : Member

Academic Rank : Professor

Research Area : Expertise : Development of Monoclonal Antibodies

Researcher Profile

Born: 1961
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Academic Rank: Professor
Education:
1991 Ph.D. (Molecular Immunology), School of Biological Sciences, The University of Surrey, UNITED KINGDOM
1987 MSc (Veterinary Microbiology), Bangladesh Agricultural University, Mymensingh
1985 DVM, Doctor of Veterinary Medicine, Bangladesh Agricultural University, Mymensingh
Scientific Interest:
Infectious diseases and immunology

Publication Summary

Journal Articles:

1. AuNP Coupled Rapid Flow-Through Dot-Blot Immuno-Assay for COVID-19 (SARS-CoV-2) Explicit IgG Antibody Revelation. Sil, B.K.; Jamiruddin, M.R.; Haq, M.A.; Khondoker, M.U.; Jahan, N.; Khandker, S.S.; Ali, T.; Oishee, M.J.; Kaitsuka, T.; Mie, M.; Tomizawa, K.; Kobatake, E.; Haque, M.; Adnan, N. AuNP Coupled Rapid Flow-Through Dot-Blot Immuno-Assay for COVID-19 (SARS-CoV-2) Explicit IgG Antibody Revelation. Preprints 2021, 2021040534 (doi: 10.20944/preprints202104.0534.v1). 

2. Assessment of a rapid pan-antibody dot test for detection of antibodies against SARSCoV-2., Haq, M. A. ., Jamiruddin, M. ., Khondoker, M. U. ., Ahmed, M. F., Khandker, S. S., Ali, T., Mostafi, M. ., Sil, B. K. ., Adnan, N. ., & Jamiruddin, M. R. . (2021). Bangladesh Journal of Medical Science, 20(5), 131–139. https://doi.org/10.3329/bjms.v20i5.55407 
3. Development and performance evaluation of a rapid in-house ELISA for retrospective sero-surveillance of SARS-CoV-2. Bijon Kumar Sil, Nowshin Jahan, Md. Ahsanul Haq, Mumtarin Jannat Oishee, Tamanna Ali, Shahad Saif Khandker, Eiry Kobatake, Masayasu Mie, Mohib Ullah Khondoker, Mohd. Raeed Jamiruddin, Nihad Adnan. PloS: Feb 2021: https://doi.org/10.1371/journal.pone.0246346. 
 4. COVID-19 Pandemic: Review of Contemporary and Forthcoming Detection Tools. Mumtarin Jannat Oishee, 1 Tamanna Ali, 1 Nowshin Jahan, 1 Shahad Saif Khandker, 1 Md Ahsanul Haq, 1 Mohib Ullah Khondoker, 2 Bijon Kumar Sil, 3 Halyna Lugova, 4 Ambigga Krishnapillai, 4 Abdullahi Rabiu Abubakar, 5 Santosh Kumar, 6 Mainul Haque, 7 Mohd Raeed Jamiruddin, 8 and Nihad Adnan9 Infect Drug Resist. 2021; 14: 1049–1082. 
5. Development and Evaluation of Two Rapid Indigenous IgG-ELISA immobilized with ACE-2 Binding Peptides for Detection Neutralizing Antibodies Against SARS-CoV-2. Bijon Kumar Sil, Nihad Adnan, Mumtarin Jannat Oishee, Tamanna Ali, Nowshin Jahan, Shahad Saif Khandker, Eiry Kobatake, Masayasu Mie, Mohib Ullah Khondoker, Md. Ahsanul Haq, Mohd. Raeed Jamiruddin. doi: https://doi.org/10.1101/2020.12.19.20248535. 
6. Longitudinal Observation of Antibody Dynamics in Three COVID-19 Patient against Four Structural SARS-CoV2 Proteins.Nihad Adnan, Mohd. Raeed Jamiruddin, Md. Ahsanul Haq, Shahad Saif Khandker, Nowshin Jahan, Tamanna Ali, Mumtarin Jannat Oishee, Zafrullah Chowdhury, Mohib Ullah Khondoker, Bijon Kumar Sil, June 2021Journal of Inflammation Research 14:2497-2506 DOI:10.2147/JIR.S313188 
7. Melatonin might be the next potential therapeutic approach for the treatment of omicron and other variants of SARS-CoV-2". Rahima Begum; A.N.M. Mamun-Or-Rashid; TanzimaTarannum Lucy; Md. Kamruzzaman Pramanik; Bijon Kumar Sil; Nobendu Mukerjee; Fouad Damiri; Mohammed Berrada; Priti Tagde; Md. Habibur Rahman (submitted)
8. Evaluation of efficacy of various immunochromatographic rapid tests for dengue diagnosis, Arshi Naz, Danish Zahid, Samina Naz Mukry, Muhammad Nadeem, Bijon Kumar Sil, Tahir Sultan Shamsi, Pak J Med Sci 2014;30(1):166-171. 
9. Use of Saliva for Early Dengue Diagnosis. Grace Yap., Bijon Kumar Sil., Lee-Ching Ng* PLOS: May 2011: Vol- 5: 5: e1046. 
10. Development of ASSURE® Dengue IgA Rapid Test for the Detection of Anti-dengue IgA from Dengue Infected Patients. Yun Ying Tan, Shamala D Sekaran1, Seok Mui Wang1, Firoz Ahmed2, Anowar Hossain2, Bijon Kumar Sil, Jour of Global Infect Dis / Jul-Sep 2011 / Vol-3 / Issue-3 
11. Evaluation of ASSURE® Dengue IgA Rapid Test using dengue-positive and dengue-negative samples. Ahmed F, Mursalin H, Alam MT, Amin R, Sekaran SD, Wang SM, Tan YY, Sil BK, Hossain MA.DiagnMicrobiol Infect Dis. 2010 Dec;68(4):339-44. 
12. Mild Illness Associated with Severe Acute Respiratory Syndrome Coronavirus Infection: Lessons from a Prospective Sero epidemiologic Study of Health-Care Workers in a Teaching Hospital in Singapore. Khek Y. Ho,1Kamaljit S. Singh,1Abdulrazaq G. Habib,1Benjamin K. Ong,1Tow K. Lim,1Eng E. Ooi,2 Bijon K. Sil,2Ai-Ee Ling,3Xin L. Bai,3andPaul A. Tambyah1. Jour Infect. Dis. 2004; 189:642-647.  
13. Healthcare Worker Seroconversion in SARS Outbreak. Pierce K. H. Chow,* EngEongOoi,†Hiang-Khoon Tan,* Kong-Wee Ong,* Bijon Kumar Sil,† Melissa Teo,* Timothy Ng,‡ and Khee-CheeSoo* EID, Vol.10, No.2 February 2004. 
14. Singh, K., Ooi, E. E.,Sil, B. K., Saw, S. & Sethi, S. (2004) Severe acute respiratory syndrome without respiratory symptoms or abnormal chest radiograph findings. Clinical Infectious Diseases38: 585-586. 
15. Isolation and serotyping of dengue viruses by mosquito inoculation and cell culture technique: an experience in Bangladesh (2004). MoniraPervin, ShahinaTubassum, Bijon Kumar Sil and Md. Nazrul Islam. WHO Bulletin Vol 27, 81-90. 
16. ShailaJabbar, Mahmud Tareq Hassan Khan, Shahabuddin M, K Choudhuri, Bijon K Sil(2004).Bioactivity studies of the individual ingredients of the Dashamularishta. Pak J Pharm Sci Jan 2004;17(1):9-17. 
17. Raj Kumar Bose, KhondokerMoazzem Hossain, Bijon Kumar Sil and Mohammed Taimur (2003). Comparative sero-evaluation of live and killed Gumboro vaccine in Broilers. ITAL. J. ANIM. SCI. Vol 2 157- 162. 
18. Identification of envelope protein epitopes that are important in the attenuation process of wild-type yellow fever virus. B.K. Sil, L.M. Dunster, T.N. Ledger, M.R. Wills, P.D. Minor and A.D.T. Barrett. Jour. Viro, 1992 July 66(7):4265-70. 
19. Immunogenicity of the experimental live attenuated Japanese cncepahlitis vaccine viruses and comparison with wild-type strains using monoclonal and polyclonal antibodies. B.K.Sil, M.R. Wills, J.X. Cao, A. Islam, B. Singh, A. Jenings and A.D.T. Barrett. Vaccine, Vol.10 329- 333, 1992. 
20. Antigenic characterization of the live attenuated Japanese encephalitis virus SA14-14-2: Examination and comparison to isolates of JE virus covering a wide geographic area. Marks. R. Wills, Bijon. K. Sil, Jing. X. Cao and ADT Barrett. Vaccine, Vol. 10, Issue 12, 861-872, 1992. 
21. Variation in the biological function of envelope protein epitopes of yellow fever vaccine viruses detected using monoclonal antibodies. T.N. Ledger, B.K. Sil, M.R. Wills, G. Lewis, R.M. Kinney and A.D.T. Barrett. Biologicals (1992) 20, 117-128. 
22. Analysis of the yellow fever virus isolated from a fatal case of vaccine-associated human encephalitis. A.D. Jennings, C.A. Gibson, B.R. Miller, J.H. Mathews, J.T. Roehrig, D.J. Wood, F. Taffs, B.K.Sil, S.N. Whiteby, T.P. Monath, P.D. Minors, P.G. Sanders and A.D.T. Barrett. Jour. Infect. Dis. 1994:169:512-8. 
23. In vitro homotypic and heterotypic interference by defective interfering particles of West Nile virus. Debnath N, Tierney R, Sil BK, Wills MR, BARRETT ADT. J Gen Virol 72: 2705-2711, 1991. 
24. Yellow fever 17DD vaccine is temperature-sensitive when grown in mosquito C6-36 cells. Ledger TN, Sil BK, Dunster LM, Stephenson JR, Minor PD, BARRETT ADT. Vaccine 10: 652-654, 1992. 
25. Passage of Japanese encephalitis virus in HeLa cells results in attenuation of virulence in mice. Cao JX, Ni H, Campbell GA, Sil BK, Ryman KD, Kitchen I, BARRETT ADT. J Gen Virol 76: 2757-2764, 1995. 
26. Evidence that the envelope protein epitope of flavivirus encodes determinants of attenuation and virulence. Alan D.T. Barrett. Lee M. Dunster, Bijon K. Sil, Neil T, Ledger, Carl A. Gibson, Peter, G. Sanders, Ernest A. Gould and Philip D. Minor. In Vaccine-90, pp 98-106. 
27. Molecular basis of attenuation and immunogenicity of a live attenuated Japanese encephalitis vaccine virus SA1414-2. Alan D.T. Barrett. Bijon K. Sil, Jing X. Cao, Rakesh Sharda, Marks R. Wills, Allison Kennedy, Ian N. Kitchen, N.Jack Burns, SorachiNitayaphan and Dennis W. Trent. In Vaccine-91, pp 259-263. 

Patents:

  1. Designing of 3 rd generation of COVID-19 (2 in 1) antigen/antibody combo Rapid test. Provisional Patent: waiting for submission
  2. Methods of Purification of SARSCoV22 Antibodies for The Early Detection And intervention of Covid-19 Infection: "Provisional" Patent Application No. 10202010972V, dated 04 November 2020.
  3. DIAGNOSTIC METHODS FOR COVID-19 INFECTION: Singapore Patent Application No: 10202006327W: dated 15 July 2021.
  4. Development of Multi-Chamber based rapid Soil Test Device: Singapore patent10201903870Y dated 29th April 2019 (Patent pending)
  5. Invention of New Shaped “Y-HULL” in combination of Mono-Hull with Catamaran- Singapore Patent: 1020191198Q dated 12th February 2019 (Patent pending).
  6. 4.Method and Kit for Detecting a Dengue Virus Infection”, WO 2016022071 A1 dated 02/11/2016
  7. Integrated Model of Mini Wind Generator with Domestic Fan for Generating Recycle Electricity. Singapore Patent Application no-10201600351U dated: 18 Jan 2016
  8. "DOUBLE-CHAMBER BI-DIRECTIONAL REVERSE FLOW DEVICE." Publication No. WO/2014/168580 was published on Oct. 16, 2014
  9. Rapid Multiline Hepatitis C virus assay (HCV-MRT) (International Publication No: WO 2011/152793 A1 dated 08/12/2011.
  10. Development of MULTI-CHAMBER Lateral Flow-based Device for MULTIPLEX Rapid Testing-Patent Pending (2015).
  11. Point of Care Test for the Detection of HEV Infection (WO/2010/107398 date 23-09-2010).
  12. Antigens capture Anti-dengue IgA (ACA-ELISA) for the detection of flavivirus specific IgA using patients’ saliva and serum. (US 20100035231 A1, Feb 11, 2010).
  13. Point of Care Test for the detection of exposure or immunity to dengue virus (International publication No: WO 2009/139725 A1, dated 19 November 2009.).
  14. Competitive Enzyme linked Immunosorbent Assay (C-ELISA) for the detection of flaviviruses specific antibody (International patent: WO/2007/106050 Publishing date: 20.09.2007).
  15. Development of rapid dengue IgG and IgA dot-blot technique (Singapore patent no. 200404253-7; dated-22/07/2004).
  16. Development of SARS antibody-based diagnostic kit using dot-blot ELISA (Singapore Patent No- 200304813-9, dated-06/08/2003).
  17. Development of MULTISURE BloodScan Rapid Test-applied for filling in Singaporedated-10-05- 2013. 2003048139
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